Optima BoneActive Brochure - Nutricaa

Optima BoneActive

Bone & Joint Health Formula

Optima BoneActive Product

400g Tin Can

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Key Features

High Bioavailable Calcium

536mg calcium per 100g (70% DV) with optimal calcium-to-phosphorus ratio for superior absorption.

Collagen Type II

Contains collagen to support joint health, cartilage integrity, and flexibility.

Complete Mineral Matrix

Magnesium (140% DV), Zinc, and Manganese for complete bone metabolism support.

Vitamin D3 Enhanced

13mcg Vitamin D (50% DV) for optimal calcium absorption and bone remodeling.

Indications for Use
  • Osteoporosis & Bone Loss - Enhanced calcium and mineral content for bone density
  • Osteoarthritis & Joint Disorders - Collagen Type II for joint support and mobility
  • Post-Surgery & Fracture Recovery - Accelerated bone healing and strength
  • Athletes & Active Lifestyle - Support for joint mobility and flexibility
Key Nutritional Facts (Per 100g)
Nutrient Amount % DV Nutrient Amount % DV
Calories 450 - Dietary Fiber 22g 79%
Total Fat 17g 22% Vitamin D 13mcg 50%
Protein 22g 44% Calcium 536mg 70%
Total Carbs 52g 19% Magnesium 367mg 140%
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Sesamin Study for Osteoporotic Fracture Healing

Clinical Study Summary: Sesamin Promotes Osteoporotic Fracture Healing

Study Overview: This study investigates sesamin, a natural phytoestrogen derived from sesame, as a safer alternative to estrogen replacement therapy for promoting fracture healing in postmenopausal osteoporosis. Traditional treatments often carry risks of serious side effects.

Mechanism: Sesamin acts as a ligand for estrogen receptor alpha (ERα), forming a hydrogen bond with residue ARG346. This activates the bone morphogenetic protein 2 (BMP2) signaling pathway, critical for bone and cartilage development.

Key Findings: Sesamin significantly enhanced angiogenesis (blood vessel formation) by upregulating VEGF and Mmp2 markers. It promoted chondrogenesis (cartilage development) and increased proteoglycan synthesis. In ovariectomized mice, oral sesamin (80 mg/kg/day) improved callus formation, bone reconnection, narrower fracture gaps, and better mechanical strength.

Conclusion: Sesamin facilitates osteoporotic fracture healing by stimulating both chondrogenesis and angiogenesis through the ERα/BMP2/SOX9 pathway, making it a promising herb-derived bioactive compound for treating fractures in postmenopausal women.

Reference: Nutrients 2022, 14, 2106 | DOI: 10.3390/nu14102106

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Request a free sample today and discover how Optima BoneActive can support your patients' bone and joint health.

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Website

www.nutricaa.com

Email

info@nutricaa.com

Phone

+8801717390779

Location

House No: 394, Road No: 29, New DOHS, Mohakhali, Dhaka - 1209
Koltapara, Gouripur, Mymensingh - 2270, Bangladesh

Product Information

Format
400g Tin Can
Flavor
Natural
Product Code
0788792139817
Servings
10 per Container
Serving Size
40g (5-6 tsp)
Units/Carton
4
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